Substituted Frozen Embryo Transfer Cycles With GnRH-agonist Supplementation

Substituted Frozen Embryo Transfer Cycles With GnRH-agonist Supplementation

The aim of this study is to compare two FET protocols by modifying the substituted FET cycle in order to maintain a higher ongoing positive pregnancy rate and thus reduce the early pregnancy loss.

Hypothesis: adding GnRH-agonist to the substituted cycle in FET treatment reduces the early pregnancy loss.

Inclusion Criteria:

• Endometrial thickness ≥ 7 mm after stimulation
• 18-45 years
• IVF/ICSI fertilisation
• BMI > 18,5 <30 kg/m2
• cycle length 25-34 days

Exclusion Criteria:

• endometrial thickness < 7 mm or no triple layer endometrium and/or functional follicles
• Uterine abnormality
• Chronic medical disease
• oocyte donation cycles