Social Deprivation and Initial Presentation of 12 Cardiovascular Diseases: a CALIBER Study

Study of heterogeneity in associations between social deprivation and the initial presentation of 12 cardiovascular diseases.

This study is part of the CALIBER (Cardiovascular disease research using linked bespoke studies and electronic records) programme funded over 5 years from the NIHR and Wellcome Trust. The central theme of the CALIBER research is linkage of the Myocardial Ischaemia National Audit Project (MINAP) with primary care (GPRD) and other resources. The overarching aim of CALIBER is to better understand the aetiology and prognosis of specific coronary phenotypes across a range of causal domains, particularly where electronic records provide a contribution beyond traditional studies. CALIBER has received both Ethics approval (ref 09/H0810/16) and ECC approval (ref ECC 2-06(b)/2009 CALIBER dataset).

Inclusion Criteria:

• One year prior to study entry (up-to-standard follow-up, CPRD quality research standard).
• 30 years or older
• Recorded sex
• Free of symptomatic CVD at inclusion.

Exclusion Criteria:

• Pregnant women in the 6 months before the eligibility date