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The purpose of this study is to determine discordant HER2/neu status of primary breast tumor and metastatic breast cancer cells at regional lymph nodes in node positive breast cancer patients.
HER2/neu status of primary breast tumor and axillary lymph nodes were tested by IHC staining. In the cases of equivocal result of IHC, FISH test were performed.
The result of HER2/neu status between primary breast tumor and axillary lymph node were analyzed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Primary Breast Tumor | Primary breast tumor were test for HER2/neu status. | ||
| Axillary Lymph Nodes. | Axillary Lymph Nodes were tested for HER2/neu status. |
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| Measure | Description | Time Frame |
|---|---|---|
| Association of HER2/neu status between primary breast tumor and axillary lymph nodes | Association of HER2/neu status between primary breast tumor and axillary lymph nodes was analyzed by using the χ2 test | up to 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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Breast Cancer Patients Stage I,II and III.
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| Name | Affiliation | Role |
|---|---|---|
| AKANIST PIYAPANT, MD.,FRCST. | National Cancer Institute, Thailand | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Cancer Institute , Thailand. | Ratchathewi | Bangkok | 10400 | Thailand |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 15317891 | Background | Cristofanilli M, Budd GT, Ellis MJ, Stopeck A, Matera J, Miller MC, Reuben JM, Doyle GV, Allard WJ, Terstappen LW, Hayes DF. Circulating tumor cells, disease progression, and survival in metastatic breast cancer. N Engl J Med. 2004 Aug 19;351(8):781-91. doi: 10.1056/NEJMoa040766. | |
| 19914540 | Background | Cristofanilli M. The biological information obtainable from circulating tumor cells. Breast. 2009 Oct;18 Suppl 3:S38-40. doi: 10.1016/S0960-9776(09)70270-X. |
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| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
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Paraffin embedded tissue blocks of primary breast tumor and axillary lymph nodes
| D017437 |
| Skin and Connective Tissue Diseases |