Axillary Nodal Burden in HER2+ and TNBC

Low Axillary Nodal Metastasis Rates in Selected HER2-Positive and Triple-Negative Breast Cancer Patients: Toward De-escalation of Sentinel Lymph Node Biopsy

This study aimed to evaluated rates of pathologic axillary nodal metastasis in patients with with early-stage HER2-positive BC or TNBC who had clinically node-negative status on preoperative ultrasonography and underwent upfront breast-conserving surgery (BCS) with axillary surgery. In addition, this study aimed to identify subgroups in which SLNB omission may be feasible.

Inclusion Criteria:

• HER2-positive breast cancer or TNBC
• Patients who received upfront breast conserving surgery with axillary surgery
• Patients who had a clinically axillary node negative disease

Exclusion Criteria:

• Patients who underwent mastectomy
• Absence of axillary nodal assessment on ultrasonography
• Patients who underwent mastectomy
• Patients who underwent mastectomy