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Obesity is very common worldwide and breathing problems at night (obstructive sleep apnea, OSA) are common in obesity. Despite the best treatment, obesity and OSA are linked to early death from heart problems. They are also associated with lower levels of physical activity. Exercise strategies for weight loss, increasing physical activity and improving fitness are needed for obesity. In Obese individuals with OSA
The information from these three projects will help us set up the optimal exercise program for obese individuals.
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| Measure | Description | Time Frame |
|---|---|---|
| Peak oxygen uptake (Peak VO2) measured at the end of the Incremental Shuttle Walk Test (ISWT) | Two Incremental Shuttle Walk tests will be performed within two hours on the same day with expired gas analysis measured by a portable gas analyser. An ISWT is conducted over a 10m course and the speed is externally paced and increases each minute. The participant is asked to continue until they are either too breathless or too tired to continue. | All outcome measures will be performed within four weeks of each other |
| Measure | Description | Time Frame |
|---|---|---|
| Six minute walk test (6MWT) | The 6MWT will be performed over a 30 m level, straight course within an enclosed corridor. The test protocol described by the American Thoracic Society will be modified to include standardized encouragement every 15 seconds to recommence walking if the participant chooses to rest during the test. Participants will be familiarized with the test prior to participating in the study and, therefore, only one test will be performed. |
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Inclusion Criteria:
Exclusion Criteria:
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Obstructive Sleep Apnea
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| Name | Affiliation | Role |
|---|---|---|
| Roger S Goldstein, MBChB | West Park Healthcare Centre | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| West Park Healthcare Centre | Toronto | Ontario | M6M 2J5 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24577643 | Derived | Evans RA, Dolmage TE, Robles PG, Goldstein RS, Brooks D. Do field walking tests produce similar cardiopulmonary demands to an incremental treadmill test in obese individuals with treated OSA? Chest. 2014 Jul;146(1):81-87. doi: 10.1378/chest.13-2060. |
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| ID | Term |
|---|---|
| D020181 | Sleep Apnea, Obstructive |
| D009765 | Obesity |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D012891 | Sleep Apnea Syndromes |
| D001049 | Apnea |
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
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| Four weeks |
| Incremental Treadmill Test (ITM) | A maximal treadmill test will be performed once with expired gas analysis. | Four weeks |
| Incremental cycle test (ICE) | A maximal symptom limited cardio-pulmonary exercise test on a cycle ergometer. | Four weeks |
| Endurance cycle ergometer | Two endurance cycle tests will performed at 60% and 80% of the maximal peak oxygen obtained on either the ICE or ITM | Four weeks |
| Endurance treadmill test | Constant speed endurance treadmill test will be performed at 60% and 80% of the peak oxygen uptake achieved on either the ITM or ICE to symptom limitation | Four weeks |
| Daily physical activity | A sensewear armband will be worn for 7 days and only taken off for showering/bathing. | Four weeks |
| D020919 |
| Sleep Disorders, Intrinsic |
| D020920 | Dyssomnias |
| D012893 | Sleep Wake Disorders |
| D009422 | Nervous System Diseases |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001519 | Behavior |