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| Name | Class |
|---|---|
| French Eso-Gastric Tumors Working Group | OTHER |
| Federation of Research in Surgery (FRENCH) | OTHER |
| AFC (Association Francophone de Chirurgie) | UNKNOWN |
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Background
Secondary objectives :
Methodology : European French-speaking retrospective multicentric study Inclusion criteria: All consecutive patients operated on, for a histologically proven carcinoma of the esophagus, the oesophago-gastric junction (Siewert type I and II), in surgical investigator centers between January 2000 and December 2010 Exclusion criteria: Siewert III type carcinoma of the oesophago-gastric junction , non surgical treatment of esophageal carcinoma Planned study period: The data will be collected over a 11-year period from January 2000 to December 2010. Follow up will be ascertained in May 2013.
Patients with an esophageal or junctional carcinoma (including SIewert type I and II) with surgical resection of the primary tumor inclusion date will be date of surgery all patients will be followed during 5 years after surgery or time of death
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Esophagectomy for cancer | Patients operated on for a cancer of the esophagus, a Siewert I or II cancer of the oesophago-gastric junction |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Esophagectomy | Procedure | Esophagectomy for esophageal cancer whatever can be the surgical approach (with or without thoracotomy, minimally invasive or not) |
|
| Measure | Description | Time Frame |
|---|---|---|
| To identify predictors of recurrence after esophageal cancer surgery | clinical factors linked to 5-year recurrence will be identify through univariable and multivariable analysis | 30 May 2012 |
| Measure | Description | Time Frame |
|---|---|---|
| 5 year recurrence free survival | events: death and recurrence at 5 years after surgery | 30 May 2012 |
| 5 year overall survival | all causes for death at 5 years after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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Patients operated on for a cancer of the esophagus , a Siewert I or II cancer of the oesophago-gastric junction
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| Name | Affiliation | Role |
|---|---|---|
| Christophe Mariette, MD, PhD | University Hospital, Lille | Study Director |
| Caroline Gronnier, MD | CHRU LILLE | Principal Investigator |
| Denis Collet, MD, PhD | University Hospital, Bordeaux | Principal Investigator |
| Bernard Meunier, MD, PhD | Rennes University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital, Lille | Lille | 59045 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25617915 | Background | Mariette C, Gronnier C, Duhamel A, Mabrut JY, Bail JP, Carrere N, Lefevre JH, Meunier B, Collet D, Piessen G; FREGAT Working Group-FRENCH-AFC; FREGAT Working Group-FRENCH-AFC. Self-expanding covered metallic stent as a bridge to surgery in esophageal cancer: impact on oncologic outcomes. J Am Coll Surg. 2015 Mar;220(3):287-96. doi: 10.1016/j.jamcollsurg.2014.11.028. Epub 2014 Dec 12. | |
| 39039292 |
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| ID | Term |
|---|---|
| D004938 | Esophageal Neoplasms |
| D004935 | Esophageal Diseases |
| ID | Term |
|---|---|
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| ID | Term |
|---|---|
| D016629 | Esophagectomy |
| ID | Term |
|---|---|
| D013505 | Digestive System Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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| 30 may 2012 |
| Predictors of postoperative mortality and morbidity after surgery | 30-day postoperative mortality and 30-day overall postoperative morbidity | 30 May 2012 |
| Impact of pCR on recurrence and survival | pathological complete response within the tumor and nodes | 30 May 2012 |
| Impact of neoadjuvant treatments on recurrence and survival | looking at the impact of neoadjuvant chemo and/or chemoradiation on oncological outcomes | 30 May 2012 |
| Impact of patient preconditioning (such as nutritional support, esophageal prosthesis, mini-invasive approach…) on outcomes | looking at the impact of nutritional support, endoscopic and surgical procedures on outcomes | 30 May 2012 |
| Derived |
| Teixeira-Farinha H, Behal H, Cailliau E, Pasquer A, Duhamel A, Thereaux J, Chalret du Rieu M, Lefevre JH, Turner K, Mantziari S, Collet D, Piessen G, Gronnier C; FREGAT Network-AFC Working Group. Impact of primary endoscopic resection on oncological outcomes after esophagectomy for cancer: a retrospective propensity score-based cohort study. Surg Endosc. 2024 Sep;38(9):5169-5177. doi: 10.1007/s00464-024-11077-2. Epub 2024 Jul 22. |
| 26135681 | Derived | Markar SR, Gronnier C, Duhamel A, Pasquer A, Thereaux J, Chalret du Rieu M, Lefevre JH, Turner K, Luc G, Mariette C; FREGAT Working Group-FRENCH-AFC. Significance of Microscopically Incomplete Resection Margin After Esophagectomy for Esophageal Cancer. Ann Surg. 2016 Apr;263(4):712-8. doi: 10.1097/SLA.0000000000001325. |
| 25379847 | Derived | Gronnier C, Trechot B, Duhamel A, Mabrut JY, Bail JP, Carrere N, Lefevre JH, Brigand C, Vaillant JC, Adham M, Msika S, Demartines N, El Nakadi I, Piessen G, Meunier B, Collet D, Mariette C; FREGAT Working Group-FRENCH-AFC; Luc G, Cabau M, Jougon J, Badic B, Lozach P, Cappeliez S, Lebreton G, Alves A, Flamein R, Pezet D, Pipitone F, Iuga BS, Contival N, Pappalardo E, Mantziari S, Hec F, Vanderbeken M, Tessier W, Briez N, Fredon F, Gainant A, Mathonnet M, Bigourdan JM, Mezoughi S, Ducerf C, Baulieux J, Pasquer A, Baraket O, Poncet G, Vaudoyer D, Enfer J, Villeneuve L, Glehen O, Coste T, Fabre JM, Marchal F, Frisoni R, Ayav A, Brunaud L, Bresler L, Cohen C, Aze O, Venissac N, Pop D, Mouroux J, Donici I, Prudhomme M, Felli E, Lisunfui S, Seman M, Petit GG, Karoui M, Tresallet C, Menegaux F, Hannoun L, Malgras B, Lantuas D, Pautrat K, Pocard M, Valleur P. Impact of neoadjuvant chemoradiotherapy on postoperative outcomes after esophageal cancer resection: results of a European multicenter study. Ann Surg. 2014 Nov;260(5):764-70; discussion 770-1. doi: 10.1097/SLA.0000000000000955. |
| D006258 |
| Head and Neck Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |