Nasal Intermittent Positive-Pressure Ventilation for Twin Infants With Respiratory Distress Syndrome

Nasal Intermittent Positive-Pressure Ventilation vs Nasal Continuous Positive Airway Pressure for Twin Infants With Respiratory Distress Syndrome

In the present study, we hypothesized that primary mode nIPPV initiated shortly after birth would decrease the incidence of intubation or death in twin infants when compared to nCPAP.

After inclusion of eligible twins infants,one of the twins was supported by nCPAP and another nIPPV.

Inclusion Criteria:

• Twins
• Clinical diagnosis of mild-moderate respiratory distress syndrome
• requiring a fraction of inspired oxigen (FiO2 ) <0.40 to keep oxygen saturation of 90%-95%
• a chest X-ray suggestive of early stage hyaline membrane disease, (i.e. mild microgranulia and air bronchogram)

Exclusion Criteria:

• pneumothorax
• pneumomediastinum
• surgical diseases
• cardiac diseases
• intraventricular hemorrage
• major congenital defects