This study will assess which of the three most common methods of wound closure in primary total knee arthroplasty (staples, interrupted vertical mattress, or running subcuticular suture) provide the best wound vascular perfusion. This can be achieve by using SPY intra-operative vascular angiography, which is commonly used in clinical practice to assess perfusion of wound closure at the clinic. By understanding the differences in perfusion afforded by different closure techniques, surgeons will then be able to select the technique that optimizes this parameter so as to avoid complications such as tissue necrosis, wound dehiscence, or infection.

Inclusion Criteria:

• ≥ 18 years old
• Primary diagnosis of osteoarthritis
• Surgical indication for index total knee arthroplasty

Exclusion Criteria:

• Previous surgery about the knee
• Systemic corticosteroid use
• Active infection of any kind or chronic infection with HIV, Hepatitis C, or Syphilis