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| ID | Type | Description | Link |
|---|---|---|---|
| Ritalin version 5 | Other Identifier | Rambam Healthcare Campus |
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| methylphenidate hydrochloride | Experimental | The study will include two sessions which will be conducted at the same time of the day, one week apart from each other. Each session will last approximately 6 hours. In each session subjects will be exposed to baseline experimental pain models and auditory tests. Then they will receive either one MP SR 20 mg tablet or an identical looking placebo. |
|
| Sugar pill | Placebo Comparator | The study will include two sessions which will be conducted at the same time of the day, one week apart from each other. Each session will last approximately 6 hours. In each session subjects will be exposed to baseline experimental pain models and auditory tests. Then they will receive either one MP SR 20 mg tablet or an identical looking placebo. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| methylphenidate hydrochloride | Drug |
| ||
| Sugar pill (placebo) |
| Measure | Description | Time Frame |
|---|---|---|
| Experimental pain intensity measured on a visual analogue scale (0-100) | 4 hours |
| Measure | Description | Time Frame |
|---|---|---|
| effect of Ritalin on auditory sensitivity, measured by the response to different auditory stimulations | 4 hours | |
| pain intensity (NPS 0-100) in response to thermal stimuli and the measures of the auditory tests. | 4 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Elon Eisenberg, MD | Rambam Helthcare Campus, Haifa, Israel 31096 | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rambam Healthcare Campus | Haifa | 31096 | Israel |
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| ID | Term |
|---|---|
| D008774 | Methylphenidate |
| D000073893 | Sugars |
| ID | Term |
|---|---|
| D010648 | Phenylacetates |
| D000146 | Acids, Carbocyclic |
| D002264 | Carboxylic Acids |
| D009930 | Organic Chemicals |
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| Drug |
|
| D010880 |
| Piperidines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D002241 | Carbohydrates |