safety evaluation of endoscopic sub-mucosal dissection with nestis enki2 system. This system is a new water jet system which allows to perform Endoscopic submucosal dissection with a bifunctional catheter (injection and cutting).

Evaluation of the ability of this system to have a complete resection of superficial tumors of the digestive tract (that is to say a resection with free lateral and deep margins without residual tumor tissue)

Evaluation of the ability of such system to inject a viscous macromolecular solution of glycerol (glycerol mix: Glycerol 10 %, Fructose 5 %, saline solution 0.9%)(27. Fujishiro M, Yahagi N, Kashimura K, et al. Comparison of various submucosal injection solutions for maintaining mucosal elevation during endoscopic mucosal resection. Endoscopy. 2004;36:579-583.)

Inclusion Criteria:

• OVER 18 YEARS OLD
• PATIENTS AGREED WITH THE STUDY
• SCORE ASA 1 OR 2
• Patient recorded in a social safety organism
• patients presenting with superficial lesions with an endoscopic indication of resection

Exclusion Criteria:

• under 18 years old
• Patients not agreed with the study
• pregnant women
• patient included in an another study
• medical treatments (radiotherapy, surgery endoscopis treatements) before the intervention
• coagulation disorders
• score asa over 3
• patients with another neoplasic lesion