Systemic lupus erythematosus is a complex disease whose evaluation in everyday practice and in clinical research requires several aspects to be taken into account, in particular the impact of disease activity on quality of life. To date, the effect of systemic lupus on quality of life has only been described using generic questionnaires. Among the specific questionnaires for systemic lupus, the LupusQol, which has been validated in French, shows interesting psychometric properties. The determinants of quality of life specifically related to the disease are still unknown and could be studied using a longitudinal cohort thanks to the French version of the LupusQol.

Inclusion Criteria:

• - Patients meeting ACR 1997 classification criteria for systemic lupus erythematosus.
• Patients able to understand written and spoken French.
• Patients aged from 18 to 75 years
• Patients who have received written and oral information about the research.

Exclusion Criteria:

• - Patients aged less than 18 years
• Patients aged more than 75 years
• Severe mental retardation Any impairment of abilities to understand that make self-evaluation impossible