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Lack of compliance of the clinical site
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The objective of this clinical study is to evaluate the influence of the Great autohemotherapy with oxygen-ozone (hyperbaric ozone therapy ) to describe the cardiovascular system in patients with resistant hypertension. The primary endpoint is the change in mean blood pressure after 10 treatments .
In addition, data are collected on the immune system as well as for food and sleep quality.
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| Measure | Description | Time Frame |
|---|---|---|
| Change of blood pressure | Primary endpoint is, that there is a changing of the middle blood pressure after 10 treatments. The blood pressure will get messured at all patients which get treated with oxygen-ozone. The aim is reached, if there is a reduction of the middle blood pressure after 10 treatments by 10 mmHg compared to the blood pressure by the patients at the baseline at beginning. | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Change of pulse | The Pulse will be measured at each follow-up. It will be measured 3 times at the dominate arm. | 3 months |
| Change of blood count, liver and nephrew values | The change of blood counts, liver and nephrew values serves as a sign for change of immune activity in a patient. Furthermore potential negative effects will be reportet as an adverse event. |
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Inclusion Criteria:
Exclusion Criteria:
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All patients which fulfill the mentioned criterias.
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| Name | Affiliation | Role |
|---|---|---|
| Panos Porikis, Phd | unafflicated | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Dr. Panos Porikis | Biblis | Hesse | 68647 | Germany |
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| ID | Term |
|---|---|
| D009122 | Muscle Hypertonia |
| ID | Term |
|---|---|
| D020879 | Neuromuscular Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
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Blood samples
| 3 months |
| Change of liver and nephrew values | 3 months |
| Change of life and Sleeping quality | Change of life and sleeping quality will be measured in a 7 scale. This questionnaire is to fill in by the patient. | 3 months |
| D013568 | Pathological Conditions, Signs and Symptoms |