Impact of Sympathetic Renal Denervation- a Study in Patients After Renal Transplantation

A Randomized Safety and Efficacy Study Investigating the Effects of Catheter-based Renal Denervation in Patients After Renal Transplantation

The study is aiming to document the safety and effectiveness of renal denervation in patients after renal transplantation with hypertension. Catheter-based renal denervation will be performed using CE marked, percutaneous Symplicity catheter.

Inclusion Criteria:

• Patient after renal transplantation (> 6 month) without resection of native kidneys
• systolic blood pressure >=150 mmHg
• on 3 or more antihypertensive medications
• Individual is 18 years of age
• Individual agrees to have all procedures performed, and is competent and willing to provide written, informed consent to participate in the registry.

Exclusion Criteria:

• secondary causes and a white coat hypertension
• renal artery abnormalities
• eGFR < 30mL/min (MDRD)
• angina
• severe Aortic valve stenosis
• Individual is pregnant, nursing or planning to be pregnant
• other