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The purpose of this study is to investigate the clinical utility of renal denervation for the treatment of refractory hypertension.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Renal Denervation | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Renal Denervation | Device |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| Safety - complications associated with delivery and/or use of the Ardian Catheter, adverse renal events, electrolyte disturbances, hemodynamic events. | Through 3 years |
| Measure | Description | Time Frame |
|---|---|---|
| Physiologic response to renal denervation (e.g., blood pressure reduction) | Through 3 years |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Henry Krum, PhD | Monash University and the Alfred Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Prairie Heart Institute | Springfield | Illinois | 62701 | United States | ||
| Hennepin County Medical Center |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24210779 | Derived | Krum H, Schlaich MP, Sobotka PA, Bohm M, Mahfoud F, Rocha-Singh K, Katholi R, Esler MD. Percutaneous renal denervation in patients with treatment-resistant hypertension: final 3-year report of the Symplicity HTN-1 study. Lancet. 2014 Feb 15;383(9917):622-9. doi: 10.1016/S0140-6736(13)62192-3. Epub 2013 Nov 7. |
| Label | URL |
|---|---|
| Medtronic Renal Denervation Program | View source |
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| Minneapolis |
| Minnesota |
| 55415 |
| United States |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | United States |