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The present research aims at examining the effectiveness of a specific set of therapist relational interventions and attitudes, called the Motive-Oriented Therapeutic Relationship (MOTR), based on Plan Analysis (Caspar, 2007) in the early-phase treatment of patients diagnosed with Borderline Personality Disorder.
The investigators intend to include N = 80 outpatients diagnosed with Borderline Personality Disorder, consulting at the Outpatient Personality Disorder Program of the Karl Jaspers Clinical Unit, in collaboration with the Institute of Psychotherapy, at the Department of Psychiatry-CHUV, University of Lausanne and in collaboration with the University of Berne, Switzerland. Patients are assigned by chance to two treatment conditions 1) Control condition (General Psychiatric Management; Gunderson & Links, 2008) and 2) MOTR-condition. The investigators hypothesize better results in the MOTR-condition, as compared to the control condition in terms of symptom reduction pre-post.
The conduct of the study represents a significant contribution to the understanding and enhancement of relationship aspects in the treatment of patients diagnosed with Borderline Personality Disorder which may be of potential benefit for these patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| General Psychiatric Management (GPM; Gunderson & Links, 2008) | Active Comparator | psychodynamic-psychiatric treatment for borderline personality disorder |
|
| GPM plus Motive-Oriented Therapeutic Relationship | Experimental | use of Plan Analysis and Motive-oriented therapeutic relationship, as add-on variable to GPM |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Psychiatric Management | Behavioral |
| ||
| Measure | Description | Time Frame |
|---|---|---|
| Outcome Questionnaire -45.2 (Lambert et al., 2004) | pre- post- intervention in a randomized controlle trial; measure of symptom reduction over 3 months | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Inventory of Interpersonal Problems (Horowitz et al., 1988) | Measure of interpersonal problems after 3 months of therapy | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Borderline Symptom List (Bohus, 2009) | Symptom reduction of borderline symptoms over 3 months of treatment | 3 months |
Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Psychiatry-CHUV, University of Lausanne | Lausanne | Canton of Vaud | 1004 | Switzerland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21451348 | Result | Kramer U, Berger T, Kolly S, Marquet P, Preisig M, de Roten Y, Despland JN, Caspar F. Effects of motive-oriented therapeutic relationship in early-phase treatment of borderline personality disorder: a pilot study of a randomized trial. J Nerv Ment Dis. 2011 Apr;199(4):244-50. doi: 10.1097/NMD.0b013e3182125d19. | |
| 24752034 | Result |
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| Motive-oriented therapeutic relationship/Plan Analysis |
| Behavioral |
|
| Kramer U, Kolly S, Berthoud L, Keller S, Preisig M, Caspar F, Berger T, de Roten Y, Marquet P, Despland JN. Effects of motive-oriented therapeutic relationship in a ten-session general psychiatric treatment of borderline personality disorder: a randomized controlled trial. Psychother Psychosom. 2014;83(3):176-86. doi: 10.1159/000358528. Epub 2014 Apr 17. |
| 25324025 | Result | Kramer U, Fluckiger C, Kolly S, Caspar F, Marquet P, Despland JN, de Roten Y. Unpacking the effects of therapist responsiveness in borderline personality disorder: motive-oriented therapeutic relationship, patient in-session experience, and the therapeutic alliance. Psychother Psychosom. 2014;83(6):386-7. doi: 10.1159/000365400. Epub 2014 Oct 16. No abstract available. |
| 33256540 | Derived | Sallin L, Geissbuehler I, Grandjean L, Beuchat H, Martin-Soelch C, Pascual-Leone A, Kramer U. Self-Contempt, the Working Alliance and Outcome in Treatments for Borderline Personality Disorder: An Exploratory Study. Psychother Res. 2021 Jul;31(6):765-777. doi: 10.1080/10503307.2020.1849848. Epub 2020 Nov 30. |
| 32368793 | Derived | Storebo OJ, Stoffers-Winterling JM, Vollm BA, Kongerslev MT, Mattivi JT, Jorgensen MS, Faltinsen E, Todorovac A, Sales CP, Callesen HE, Lieb K, Simonsen E. Psychological therapies for people with borderline personality disorder. Cochrane Database Syst Rev. 2020 May 4;5(5):CD012955. doi: 10.1002/14651858.CD012955.pub2. |
| 29482597 | Derived | Penzenstadler L, Kolly S, Rothen S, Khazaal Y, Kramer U. Effects of substance use disorder on treatment process and outcome in a ten-session psychiatric treatment for borderline personality disorder. Subst Abuse Treat Prev Policy. 2018 Feb 26;13(1):10. doi: 10.1186/s13011-018-0145-6. |
| ID | Term |
|---|---|
| D001883 | Borderline Personality Disorder |
| ID | Term |
|---|---|
| D010554 | Personality Disorders |
| D001523 | Mental Disorders |
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