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| ID | Type | Description | Link |
|---|---|---|---|
| 247/UN7.5.4/HK/2022 | Other Grant/Funding Number | Medical Faculty Diponegoro University Grant 2022 |
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| Name | Class |
|---|---|
| Faculty of Medicine University of Diponegoro, Indonesia | UNKNOWN |
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In the context of therapy for Borderline Personality Disorder, our department had conduct a study titled "The Effectiveness of Dialectical Behavioral Group Psychotherapy Compared to Supportive Individual Psychotherapy in Patients with Borderline Personality Disorder: A Study of Therapeutic Alliance, Depression, Cognitive Function, Impulsivity, Suicide Risk, BDNF Levels, NFkB Levels, SOD Levels."
Psychotherapy for Borderline Personality Disorder provided weekly for 13 weeks. Patients have given a logbooks. Researchers monitored patients weekly by telephone and monitor them during outpatient visits in the second, fourth, sixth, eighth, and twelfth weeks. Blood samples were taken before and 13 weeks after treatment. During the study, patients were advised not to consume any medications or herbal remedies outside of those prescribed by the doctor and recorded in the study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| DBT group psychotherapy | Experimental | 13 weeks, one session per week. Each week, 2-hour dialectical therapy group session for 5 patients per group. |
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| Suportive psychotherapy | Active Comparator | 13 weeks, one session per week. Each week, one 30-minute session of individual supportive psychotherapy. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| DBT group psychotherapy | Behavioral | 13 weeks, one session per week. Each week, one 2-hour dialectical therapy group session for 5 patients in a group. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Therapeutic Alliances with California Psychotherapy Alliance Scales (CALPAS) | California Psychotherapy Alliance Scales (CALPAS) score. A higher CALPAS (California Psychotherapy Alliance Scale) score indicates a stronger, more positive therapeutic alliance between a patient and their therapist. The California Psychotherapy Alliance Scale (CALPAS) uses a 7-point Likert scale for its 24 items, ranging from 1 ("not at all") to 7 ("very much so"). Minimum score 24 and maximum score 168. | 13 weeks |
| Depression with GRID Hamilton Depression Rating Scale (GRID HAM-D) | GRID Hamilton Depression Rating Scale (GRID HAM-D) score, interval, higher total scores indicating greater severity of depression. Minimum Score: 0 (No depression) Maximum Score: 52 (Severe depression) | 13 weeks |
| cognitive function with Montreal Cognitive Assesment versi Indonesia (MoCA-Ina) | Montreal Cognitive Assesment Indonesian version (MoCA-Ina) score, interval. A 30-point screening tool validated to detect mild cognitive impairment (MCI) and dementia in Indonesia, with a score of 26 or higher considered normal. | 13 weeks |
| impulsivity with Barrat Impulsiveness Scale (BIS11) | Barrat Impulsiveness Scale (BIS11) score, interval, Higher scores indicate greater impulsivity, with 30-51 indicating low, 52-71 average, and 72+ high impulsivity. | 13 weeks |
| Suicide Risk with Columbia Suicide Severity Rating Scale (CSSRS) | Columbia Suicide Severity Rating Scale (CSSRS) score, interval, Any "Yes" answer to behavior or ideation requires further clinical assessment. | 13 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| NFkB Levels in ng/ml | ratio scale, nanogram/mililiter | 13 weeks |
| BDNF level in pg/ml | BDNF level in picogram/mililiter, ratio scale | 13 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| M.I. Widiastuti MIW Widiastuti, Prof. dr.PAK(K), Sp.S(K), M.Sc | Medical Faculty Diponegoro University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Medical Faculty Diponegoro University | Semarang | Central Java | 50275 | Indonesia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31955054 | Background | MacDowell KS, Marsa MD, Buenache E, Villatoro JML, Moreno B, Leza JC, Carrasco JL. Inflammatory and antioxidant pathway dysfunction in borderline personality disorder. Psychiatry Res. 2020 Feb;284:112782. doi: 10.1016/j.psychres.2020.112782. Epub 2020 Jan 11. |
| Label | URL |
|---|---|
| ethics committee RSUP dr.Kariadi website | View source |
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The data are not publicly available due to privacy or ethical restrictions. The dataset involves sensitive information from minors regarding mental health, and sharing it publicly would compromise participant confidentiality as per the ethical approval obtained.
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Randomization was performed to assign the research sample to either the treatment group (Dialectical Behavior Therapy Group) or the control group (Supportive Individual Psychotherapy).
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Each patient was assigned an identification number, and the researcher who drew blood did not know whether the patient was in the treatment group or the control group
| Supportive Psychotherapy | Behavioral | 13 weeks, one session per week. Each week, one 30-minute session of individual supportive psychotherapy |
|
| SOD levels in ng/ml | ratio scale, nanogram/mililiter | 13 weeks |
| ID | Term |
|---|---|
| D001883 | Borderline Personality Disorder |
| D003863 | Depression |
| D007175 | Impulsive Behavior |
| ID | Term |
|---|---|
| D010554 | Personality Disorders |
| D001523 | Mental Disorders |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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