Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Hemodialysis keeps patients with renal failure alive but does not restore normal health. Retention of chemicals that bind to plasma proteins and are therefore poorly removed by dialysis may contribute to ill health in patients receiving conventional treatment. This proposal will test the effect of a new method designed to improve the removal of protein-bound solutes during dialysis. The effects on blood chemical levels of two different dialysis prescriptions will be tested in patients already undergoing nocturnal in-center hemodialysis three times weekly.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| high dialysate flow, larger dialyzer | Experimental | high dialysate flow, larger dialyzer |
|
| low dialysate flow, smaller dialyzer | Active Comparator | low dialysate flow, smaller dialyzer |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| low dialysate flow, smaller dialyzer | Other | The subject will receive dialysis on the usual schedule and for the usual time but with a lower than usual dialysate flow and small dialyzer. |
| Measure | Description | Time Frame |
|---|---|---|
| Plasma levels of the chemical p-cresol sulfate | Participants will be followed for 2-3 weeks on different dialysis prescriptions and plasma chemical levels will be measured at the end of this period. |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| tim meyer, md | Contact | 650-852-3314 |
| Name | Affiliation | Role |
|---|---|---|
| Timothy W Meyer, MD | PAIRE | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Satellite Redwood City | Recruiting | Redwood City | California | 94063 | United States |
| Type | Date | Date Unknown |
|---|---|---|
| Release | Mar 28, 2019 | |
| Reset | Jun 21, 2019 |
Not provided
Not provided
| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Mar 28, 2019 | Jun 21, 2019 |
Not provided
Not provided
Not provided
Not provided
Not provided
| high dialysate flow, larger dialyzer | Other | The subject will receive dialysis on the usual schedule and for the usual time but with a higher than usual dialysate flow and large dialyzer. |
|
| Stanford University | Recruiting | Stanford | California | 94301 | United States |
|