Persistent Atrial Fibrillation Ablation Trial

Persistent Atrial Fibrillation Ablation Trial

Persistent atrial fibrillation (AF) is a common and distressing condition, that can cause significant symptoms. AF ablation is a recognised technique to treat persistent AF, but can be technically difficult. This study compares percutaneous ablation to thoracoscopic surgical AF ablation.

Inclusion Criteria:

• Symptomatic persistent or long-standing AF suitable for AF ablation.
• Age over 18 years old.
• Informed consent to participate in this study.

Exclusion Criteria:

• Pre-existing ILRs or permanent pacemakers that do not allow for continuous monitoring for AF occurrence, or are not MRI-safe.
• Unable to undergo general anaesthesia for AF ablation.
• Previous cardiac surgery, such as coronary artery bypass grafting or valvular surgery.
• Scheduled for elective cardiac surgery, such as coronary artery bypass grafting or valvular surgery.
• Previous thoracic surgery.
• Participation in a conflicting study.
• Potential participants who are mentally incapacitated and cannot consent or comply with follow-up
• Pregnancy
• Other cardiac rhythm disorders