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This study is designed to evaluate whether a specific visuospatial training task will change gait performance of Parkinson's disease (PD) patients in doorways, specifically freezing of gait.
This study is a randomized, prospective, single-blinded six-week study in PD patients with freezing of gait (FOG).
This study will involve 2 study groups:
Group A - training group; Group B - no training group/controls.
Both groups will complete a gait evaluation and neuropsychological testing. Group A will also practice an in-home visuospatial task for 30 minutes, 4-6 days per week for six weeks. Group B will not complete the in-home tasks.
Participation in this study is expected to last 6-8 weeks.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Training Group | Active Comparator | There are 2 study visits. Subjects in this group will complete the following: Visit 1
In-home •For 6 weeks at home, complete the in-home visual problem-solving tasks as instructed at Visit 1 Visit 2
|
|
| Non Training Group | Placebo Comparator | There are 2 study visits. Subjects in this group will complete the following: Visit 1
Visit 2
|
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Tower of Hanoi | Device |
| ||
| Placebo group - non use of Tower of Hanoi |
| Measure | Description | Time Frame |
|---|---|---|
| Double Limb Support (DLS) | Primary outcome will be the percent of the gait cycle spent in DLS. This will be evaluated using a GaitRite via a continuous walk, with subjects walking an 18-20 meter oval loop three times continuously. | 6 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Mark Stacy, MD | Duke University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Duke University Medical Center | Durham | North Carolina | 27705 | United States |
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| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| Other |
|
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |