Oral Glucose Stimulation in Normal-weight and Obese Volunteers

Oral Glucose in Normal-weight and Obese Volunteers

The objective of this study is to examine gastric emptying and satiety hormones after oral glucose stimulation in 2 different concentrations in normal-weight and obese patients.

Inclusion Criteria:

• Healthy normal weight subjects with a body-mass index of 19.0-24.5 or healthy obese subjects with a body-mass index of > 30
• Normal eating habits
• Age 18-40 years
• Stable body weight for at least three months

Exclusion Criteria:

• Smoking
• Substance abuse
• Regular intake of medications (except for oral contraceptives)
• Medical or psychiatric illness
• Any abnormality detected during the screening procedure
• history of gastrointestinal disorders
• food allergies