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Investigation of the training effects following 8 weeks of high-intensity interval training (HIT)in combination with side-alternating whole-body vibration compared to conventional HIT or side-alternating whole-body vibration. The adaptations are investigated on a molecular (muscle biopsy of the M. vastus lateralis) and systemic (e.g. cycling, jumping mechanography, dynamometry) level. In addition, the acute effects of the first and last training session will be investigated on a molecular (e.g. satellite cell activation, mRNA abundance) and systemic (e.g. ventilatory ga exchange, heart rate, rating of perceived exertion) level.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 4x4 min HIT | Active Comparator | Conventional 4x4 min high-intensity interval training |
|
| 4x4 min HIT + WBV (18 Hz) | Experimental | 4x4 min high-intensity interval training in combination with whole-body vibration at 18 Hz during the active rest |
|
| 4x4 min HIT + WBV (30 Hz) | Experimental | 4x4 min high-intensity interval training in combination with whole-body vibration at 30 Hz during the active rest |
|
| whole-body vibration at 30 Hz | Active Comparator | 4x3 min whole-body vibration at 30 Hz |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 4x4 min HIT | Other | Conventional 4x4 min high-intensity interval training |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in Critical Power | The differences in changes in Critical Power [Watts] are compared between the 4 training groups. For this purpose, participants complete before and after the training intervention an incremental cycling ramp test and 4 cycling constant-load tests. | 8 weeks intervention |
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Inclusion criteria: - male
Exclusion criteria: - female
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| Name | Affiliation | Role |
|---|---|---|
| Hans H Jung, Prof MD | University Hospital Zurich, Division of Neurology | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital Zurich, Division of Neurology | Zurich | Canton of Zurich | 8091 | Switzerland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25679998 | Derived | Mueller SM, Aguayo D, Zuercher M, Fleischmann O, Boutellier U, Auer M, Jung HH, Toigo M. High-intensity interval training with vibration as rest intervals attenuates fiber atrophy and prevents decreases in anaerobic performance. PLoS One. 2015 Feb 13;10(2):e0116764. doi: 10.1371/journal.pone.0116764. eCollection 2015. |
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| ID | Term |
|---|---|
| D015438 | Health Behavior |
| ID | Term |
|---|---|
| D001519 | Behavior |
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| 4x4 min HIT + WBV (18 Hz) |
| Other |
4x4 min high-intensity interval training in combination with whole-body vibration at 18 Hz during the active rest |
|
| 4x4 min HIT + (30 Hz) | Other | 4x4 min high-intensity interval training in combination with whole-body vibration at 30 Hz during the active rest |
|
| whole-body vibration at 30 Hz | Other | 4x3 min whole-body vibration at 30 Hz |
|