Intra-articular Corticosteroid Injection Compared With Single-Shot Hyaluronic Acid for Treatment of Osteoarthritis Knee

Intra-articular Corticosteroid Injection Compared With Single-Shot Hyaluronic Acid for Treatment of Osteoarthritis Knee: A Prospective, Double-blind Randomized Controlled Trial

Corticosteroid and Hylan G-F 20 are both effective in improving pain and function of osteoarthritic knee patients.

Corticosteroid and Hylan G-F 20 are both effective in improving pain and function of osteoarthritic knee patients up to 6 months.

Inclusion Criteria:

• Clinical diagnosis of knee OA
• Knee pain for most days of the prior month
• Radiographic evidence consistent with knee OA
• Aged between 40 and 80 years old

Exclusion Criteria:

• Lumbar spondylosis
• Gross deformity of the knee
• Co-existent inflammatory or crystal arthritis
• Prior knee surgery
• Injury to the knee in the preceding 6 months
• Any intra-articular injection in the preceding 3 months
• Pregnant or Lactating
• Current infection in the affected knee
• Inability to provide informed consent