Real-time fMRI Neurofeedback for Treatment of Parkinson's Disease

Real-time fMRI Neurofeedback for Treatment of Parkinson's Disease

The aim of the study is to train patients with Parkinson's Disease to increase activity in a brain area that is involved in the control of motor functions with the use of a technique called real-time fMRI neurofeedback (NF) along with regular physical exercise. This will be a randomised and controlled clinical trial to evaluate the benefits of a novel treatment. The investigators expect NF training along with physical exercise practise to better improve motor functions compared to physical exercise alone.

Inclusion Criteria:

• People with Parkinson's Disease
• Hoehn and Yahr stages 1-3 of the disease

Exclusion Criteria:

• Patients with dementia or significant comorbidity
• those who fail the safety screening to go into an MRI scanner
• those who cannot travel to the University