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The purpose of this research study is to determine how different meal patterns influence the absorption of beneficial plant pigments (carotenoids) from vegetables. The hypothesis is that carotenoid absorption will be lower when daily vegetables are consumed in one meal compared two smaller meals throughout the day.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Meal Pattern Treatment A | Experimental | A large vegetable salad (262g) and with a moderate amount of canola oil (8g) was consumed over a two meal period as designated by treatment group A. |
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| Meal Pattern Treatment B | Experimental | A large vegetable salad (262g) and with a moderate amount of canola oil (8g) was consumed over a two meal period as designated by treatment group B. |
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| Treatment Group C | Other | A large vegetable salad (262g) and with a moderate amount of canola oil (8g) was consumed over a two meal period as designated by treatment group C. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Meal Pattern Treatment A | Other | In treatment A, subjects consumed 100% of salad vegetables and canola oil in the first meal and 0% in the second. Additional protein-rich "chef's salad" ingredients were distributed equally between meals. |
| Measure | Description | Time Frame |
|---|---|---|
| Area under the concentration (AUC) vs time curve for carotenoids in the triglyceride-rich lipoprotein (TRL) fraction of plasma. | 0, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12 hours post dose |
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Inclusion criteria:
Exclusion criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Mario Ferruzzi, PhD | Purdue University | Principal Investigator |
| Wayne Campbell, PhD | Purdue University | Principal Investigator |
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| Meal Pattern Treatment B | Other | In treatment B, subjects consumed 50% of salad vegetables and canola oil in the first meal and 50% in the second. Additional protein-rich "chef's salad" ingredients were distributed equally between meals. |
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| Meal Pattern Treatment C | Other | In treatment C, subjects consumed 75% of vegetables and oil in the first meal and 25% in the second. Additional protein-rich "chef's salad" ingredients were distributed equally between meals. |
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