Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The study explores the feasibility of Eye-Movement-Desensitization and Reprocessing (EMDR) in non-specific chronic back pain.
The study explores the feasibility of Eye-Movement-Desensitization and Reprocessing (EMDR) in non-specific chronic back pain in a randomized controlled trial (RCT) with 6 months follow-up. The treatment consists of 12-sessions EMDR a 60 minutes using eye-movements for bilateral stimulation in addition to treatment as usual (TAU) that is compared to TAU alone.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Eye-Movement-Desensitization-Reprocessing | Experimental | Eye-Movement-Desensitization-Reprocessing |
|
| Treatment as usual (control group) | No Intervention | treatment as usual |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Eye-Movement-Desensitization-Reprocessing | Behavioral |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in pain intensity | Numerical rating scale 0-10 | Change from Baseline Pain intensity at average 6 months |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| functional and structural changes in fMRI | Change from Baseline fMRI at average 6 months | |
| Change in the pain experience scale - Pain affect | Geisser et al., 1996 | Change from Baseline pain experience scale levels at average 6 months |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Wolfgang Eich, Prof. Dr. | University Hospital Heidelberg | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital Heidelberg | Heidelberg | Baden-Wurttemberg | 69120 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28066274 | Derived | Gerhardt A, Leisner S, Hartmann M, Janke S, Seidler GH, Eich W, Tesarz J. Eye Movement Desensitization and Reprocessing vs. Treatment-as-Usual for Non-Specific Chronic Back Pain Patients with Psychological Trauma: A Randomized Controlled Pilot Study. Front Psychiatry. 2016 Dec 20;7:201. doi: 10.3389/fpsyt.2016.00201. eCollection 2016. | |
| 23987561 |
| Label | URL |
|---|---|
| Consortium LOGIN | View source |
Not provided
Not provided
| ID | Term |
|---|---|
| D057169 | Eye Movement Desensitization Reprocessing |
| ID | Term |
|---|---|
| D003887 | Desensitization, Psychologic |
| D001521 | Behavior Therapy |
| D011613 | Psychotherapy |
| D004191 | Behavioral Disciplines and Activities |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Change in the Hannover functional ability questionnaire (FFbH) - disability | Kohlmann et al., 1996 | Change from Baseline disabilty levels at average 6 months |
| Change in Quantitative sensory testing (QST)profiles | According to the protocol by Rolke et al. (2006), developed within the Germany Research Network on Neuropathic Pain (DFNS) | Change from Baseline QST profile at average 6 months |
| Change in Conditioned Pain Modulation | difference in pressure pain threshold before and after oscillating heat (2 min.) | Change from Baseline conditioned pain modulation activity at average 6 months |
| Change in Plasma endocannabinoids and lipids | Plasma levels: AEA (ng/ml), 2-AG (ng/ml), AA (ng/ml), PEA (ng/ml), OEA (ng/ml), AEA (pmol/g), 2-AG (pmol/g), AA (nmol/g), PEA (pmol/g), OEA (pmol/g), | Change from Baseline endocannabinoids and lipids at average 6 months |
| Change in plasma nerve growth factor levels | Plasma levels in (pg/ml) | Change from Baseline NGF levels at average 6 months |
| Change in pain drawing/ the spatial extent of the pain | Change from Baseline Pain extent at average 6 months |
| Change in West Haven-Yale multidimensional pain inventory scores | Flor et al., 1990 | Change from Baseline West Haven-Yale multidimensional pain inventory scores at average 6 months |
| Change in chronic pain grade | von Korff er al., 1992 | Change from Baseline chronic pain grade at average 6 months |
| Change in Resilience Scale (RS-11) scores | Schumacher et al., 2004 | Change from Baseline resilience scores at average 6 months |
| Change in Hospital Anxiety and Depression Scale scores | Zigmond & Snaith, 1983 | Change from Baseline anxiety and depression levels at average 6 months |
| Change in Health Survey scores | SF-12 | Change from baseline quality of life level at average 6 months |
| Change in somatization scores | SCL-90R | Change from Baseline somatization scores at average 6 months |
| Change in medication intake | Change from Baseline medication intake at average 6 months |
| Change in dissociation scores | DES/FDS-20 | Change from Baseline dissociation at average 6 months |
| Change in Post Traumatic Diagnostic Scale | Change from Baseline post traumatic diagnostic scale levels at average 6 months |
| Patient global impression of change | after on average 6 months of treatment |
| Recruitment potential | % of patients eligible for inclusion that give written informed consent | 6 months |
| Retention rate | % of patients that finish treatment, including pre- and post-evaluation | over average 6 months of treatment |
| Tesarz J, Gerhardt A, Leisner S, Janke S, Hartmann M, Seidler GH, Eich W. Effects of eye movement desensitization and reprocessing (EMDR) on non-specific chronic back pain: a randomized controlled trial with additional exploration of the underlying mechanisms. BMC Musculoskelet Disord. 2013 Aug 30;14:256. doi: 10.1186/1471-2474-14-256. |