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Some evidences have shown that probiotics are effective in the treatment of irritable bowel syndrome. Because few evidences are available in our population, we investigated if probiotics are effective in our patients as well. We hypothesize that the probiotic Lactol which contains Lactobacillus Sporogenes reduces the symptoms of irritable bowel syndrome.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Lactol | Experimental |
| |
| Placebo | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lactol | Drug | The Symbiotic Lactol® (Bioplus Life Sciences Pvt.) was applied 3 times a day for 3 months. Lactol is composed of the followings; Lactobacillus Sporogenes (15 × 107 Spores), Fructo-Oligosaccharides, Microcrystalline Cellulose, Sodium starch Glycolate, Povidone, Hypermellose Stearate, Sillicon Dioxide, and Propylene Glycol. |
| Measure | Description | Time Frame |
|---|---|---|
| Abdominal pain | Abdominal pain was assessed by Rome III questionnaire at baseline and then after 3 months. | Up to 3 months |
| Constipation | Constipation was assessed by Rome III questionnaire at baseline and then after 3 months. | Up to 3 months |
| Diarrhea | Diarrhea was assessed by Rome III questionnaire at baseline and then after 3 months. | Up to 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Mozhdeh Zahiri, MD | Islamic Azad University, Najafabad Branch | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shariati Hospital | Isfahan | Isfahan | Iran |
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| ID | Term |
|---|---|
| D043183 | Irritable Bowel Syndrome |
| D005767 | Gastrointestinal Diseases |
| ID | Term |
|---|---|
| D003109 | Colonic Diseases, Functional |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D004066 | Digestive System Diseases |
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| Placebo | Drug | Placebo pill was applied 3 times a day for 3 months |
|