Stenting for Symptomatic Intracranial Artery Stenosis Registry in China

Stenting for Symtomatic Intracranial Artery Stenosis Registry in China

Stenting for systematic Intracranial artery stenosis is challenged recently, especially for safety. This registry is aimed to explore the safety profile during peri-operation period in Stenting procedures for systematic Intracranial artery stenosis in Chinese population in real world.

Inclusion Criteria:

• 18-80 year old
• medical failure patient with systematic Intracranial artery stenosis
• More than 3 weeks after most recent ischemic stroke
• Digital Subtraction Angiography(DSA) showed ≥70% stenosis in target intracranial artery
• Imaging test within 1 week showed bad collateral circulation in target vessel area
• Diseased vessel diameter≥2mm, length <15mm, distal vessel is normal

Exclusion Criteria:

• Diffused intracranial stenosis

• Acute stroke or TIA within 3 weeks

• Pure penetrating branch stenosis showed by cerebral imaging

• Non-atherosclerosis pathology for the stenosis

• Intracranial hemorrhage in target vessel area within 6 weeks; or potential cardiac thrombus source

• Intracranial tumor, arterial aneurysm or intracranial arteriovenous malformation

  •>50% stenosis in extracranial carotid artery or vertebral artery in operation side; Known contradiction to heparin, aspirin, clopidogrel, anesthesia or contrast; hemoglobin <10g/dl，platelet count <100000

• Modified Rankin score ≥3 related to target vessel;

• INR(International Normalized Ratio)>1.5(irreversible），persist hemorrhage risk; life expectancy < 1year

• Pregnant or beast-feeding

• Not suitable for endovascular stenting judged by Indication Judgement Committee