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The specific aim of this study is to use MRI methods to evaluate and compare brain structure and function in two groups of full-term neonates at two-weeks of age: those born of obese mothers and those born to normal weight mothers.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Normal weight- Non Maternal obesity | Full-term neonates at 2 weeks of age born to normal weight mothers | ||
| Obese- Obese Mothers | Full-term neonates at two weeks of age born of obese mothers |
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| Measure | Description | Time Frame |
|---|---|---|
| Brain Structure | We will use high resolution volumetric magnetic resonance imaging (MRI) and Diffusion tensor imaging (DTI) to measure the brain structure of 2 week old infants | Age 2 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Brain Function | We will use high resolution Resting state functional magnetic resonance imaging (rsfMRI) to measure the brain function of 2 week old infants | Age 2 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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Full term neonates born from obese or lean mothers enrolled in the Glowing study (IRB#110889)
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| Name | Affiliation | Role |
|---|---|---|
| Xiawei Ou, PhD | Arkansas Children's Nutrition Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Arkansas Children's Nutrition Center | Little Rock | Arkansas | 72203 | United States |
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