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The investigators performed a 12-week, randomized, double-blind, placebo-controlled crossover human trial to evaluate the efficacy and safety of chungkookjang on improvement of metabolic syndrome. The investigators measured decrement of body fat parameters, including Body Fat Mass, Percent Body Fat, Fat Free Mass, Weight and BMI(body mass index), and monitored their blood pressure.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Chungkookjang | Experimental | Chungkookjang(35g/day) |
|
| Placebo | Placebo Comparator | Placebo(35g/day) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Chungkookjang | Dietary Supplement |
|
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Body Fat Mass | Body Fat Mass was measured in study visit 1(0 week) and visit 3(12 week). | 12 weeks |
| Changes in Percent Body Fat | Percent Body Fat was measured in study visit 1(0 week) and visit 3(12 week). | 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Glucose | Glucose was measured in study visit 1(0 week) and visit 3(12 week). | 12 weeks |
| Changes in Cholesterol | Cholesterol was measured in study visit 1(0 week) and visit 3(12 week). |
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Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Obesity Research Center of Chonbuk National University | Jeonju | Jeollabuk-do | 560-822 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 27302672 | Derived | Byun MS, Yu OK, Cha YS, Park TS. Korean traditional Chungkookjang improves body composition, lipid profiles and atherogenic indices in overweight/obese subjects: a double-blind, randomized, crossover, placebo-controlled clinical trial. Eur J Clin Nutr. 2016 Oct;70(10):1116-1122. doi: 10.1038/ejcn.2016.77. Epub 2016 Jun 15. | |
| 24171779 |
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| ID | Term |
|---|---|
| D024821 | Metabolic Syndrome |
| ID | Term |
|---|---|
| D007333 | Insulin Resistance |
| D006946 | Hyperinsulinism |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
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| ID | Term |
|---|---|
| C525760 | chungkookjang |
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| Placebo |
| Dietary Supplement |
|
|
| 12 weeks |
| Back HI, Ha KC, Kim HM, Kim MG, Yu OK, Byun MS, Jeong DY, Jeong SY, Cha YS, Park TS. The influence of the Korean traditional Chungkookjang on variables of metabolic syndrome in overweight/obese subjects: study protocol. BMC Complement Altern Med. 2013 Oct 31;13:297. doi: 10.1186/1472-6882-13-297. |
| D009750 |
| Nutritional and Metabolic Diseases |