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This research aims to compare between bandage contact lens and pressure patching in reducing size of erosion area and pain scale in corneal erosion patients as well as its complications.
This is a randomized open-label clinical trial in patients with mechanical corneal erosion. Subjects were selected to use bandage contact lens (Senofilcon A) or pressure patching. All subjects received combination of Polymyxin B, Neomycin, and Gramicidin eye drops and 0,5% Tropicamide eye drops. Evaluation was done 24 hours after treatment
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Bandage contact lens group | Experimental | subject received antibiotic eye drops (combination of Polymyxin B, neomycin and gramicidin, q.i.d), and cycloplegic eye drops (tropicamide 0,5 %, q.d) and bandage contact lens. Bandage contact lenses maintained for 24 hours. Antibiotic eye drops were instilled without removing the contact lenses |
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| Pressure patching group | Active Comparator | Subject received antibiotic eye drops (combination of Polymyxin B, neomycin and gramicidin, q.i.d), and cycloplegic eye drops (tropicamide 0,5 %, q.d) and pressure patching. Pressure patching maintained for 24 hours and only opened for drug application. Subject and their families were educated on how to perform a good pressure patching |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bandage contact lens | Device | Bandage contact lens : contact lenses (material senofilcon A; base curve 8,8 mm; power - 0,50; diameter 14 mm) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Size of corneal erosion area | Corneal erosion area is the multiplication of the long and short axis of corneal erosion, as measured using a caliper, with the help of fluorescein and cobalt blue slit lamp beam | 24 hour |
| Measure | Description | Time Frame |
|---|---|---|
| Pain scale | Pain scale assessment conducted using the Visual Analogue Scale (VAS) subjectively | 24 hour |
| Measure | Description | Time Frame |
|---|---|---|
| Complication | Complication of corneal erosion (e.g. conjunctivitis, keratitis, corneal ulcer) | 24 hour |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ni Nyoman Triharpini, MD | Department of Ophthalmology, Medical Faculty Udayana University / Sanglah Public General Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Depatment of Ophthalmolohy, Medical Faculty, Udayana University / Sanglah Public General Hospital | Denpasar | Bali | 80114 | Indonesia |
| Type | Date | Date Unknown |
|---|---|---|
| Release | Apr 3, 2013 | |
| Reset | May 17, 2013 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Apr 3, 2013 | May 17, 2013 |
| ID | Term |
|---|---|
| D003316 | Corneal Diseases |
| ID | Term |
|---|---|
| D005128 | Eye Diseases |
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| Pressure patching | Device | Pressure patching : using 2 pieces of sterile gauze. The first gauze placed vertically and the second placed horizontally, then fixed with adhesive tape so that eyelid can not move. |
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