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The purpose of this study is to investigate the effect of a meal containing different doses of L-arabinose, on the intestinal sucrase activity after intake We measure this by measuring the glucose, insulin and c-peptide after meals. Other measurements are made (glucagon and GLP-1) to explain the correlations.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 0% arabinose meal sucrose/starch | Experimental | A meal containing a bon with butter and marmalade, a cup cake, The and water |
|
| 5 % arabinose meal sucrose/starch | Other | A meal containing a bon with butter and marmalade, a cup cake, The and water |
|
| 10 % arabinose meal sucrose/starch | Other | A meal containing a bon with butter and marmalade, a cup cake, The and water |
|
| 0 % arabinose meal Starch | Other | A meal containing two bons with butter and cheese, The and water |
|
| 5 % arabinose meal starch | Other | A meal containing two bons with butter and cheese, The and water |
|
| 10 % arabinose meal starch |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| L-arabinose - effect on glucose metabolism | Dietary Supplement | L-arabinose is mixed into the dough of the buns and cup cakes |
|
| Measure | Description | Time Frame |
|---|---|---|
| Glucose | Level of glucose over time, The AUC, the peak value and time to peak | -15, 0, 15, 30, 45, 60, 90, 120, 180 min |
| Insulin | Level of insulin over time, the AUC, the peak value and time to peak | -15, 0, 15, 30, 45, 60, 90, 120, 180 min |
| C-peptide | Level of c-peptide over time, The AUC, the peak value and time to peak | -15, 0, 15, 30, 45, 60, 90, 120, 180 min |
| Measure | Description | Time Frame |
|---|---|---|
| Glucagon | Level of glucagon over time, The AUC, the peak value and time to peak | -15, 0, 15, 30, 45, 60, 90, 120, 180 min |
| GLP-1 | Level of GLP-1 over time, The AUC, the peak value and time to peak |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jens Rikardt Andersen, MD, lector | Unit of Nutrition 5711, Rigshospitalet, Blegdamsvej 9, 2100 København Ø | Study Director |
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| Other |
A meal containing two bons with butter and cheese, The and water |
|
| -15, 0, 15, 30, 45, 60, 90, 120, 180 min |