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The impact of Hysterectomy with preservation of the ovaries on ovarian function has long been controversial. studies have shown conflicting data regarding ovarian function after simple Hysterectomy.
In recent years, there is a growing evidence that Salpingectomy or Fimbriectomy may have preventive value reducing Ovarian and Primary Peritoneal carcinoma, but the safety and the consequences regarding ovarian function have yet to be established.
The aim of this study is to evaluate ovarian function after Hysterectomy alone Vs. Hysterectomy combined with salpingectomy or fimbriectomy
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hysterectomy | No Intervention | Hysterectomy without oophorectomy or salpingectomy | |
| Hysterctomy with salpingectomy or fimbriectomy | Experimental | Salpingectomy or Fimbriectomy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Salpingectomy or Fimbriectomy | Procedure |
|
| Measure | Description | Time Frame |
|---|---|---|
| Ovarian function | ovarian function measured by FSH , AMH and follicule count on ultra-sound | 60 days post-operative |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Alon Ben- Arie, MD | Contact | 00-972-50-2460001 | abenarie@hotmail.com | |
| Yael Naaman, MD | Contact | 00-972-52-3499377 | yaelnaa@gmail.con |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kaplan Medical Center | Recruiting | Rehovot | Israel |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 7409710 | Background | Maseela T, Scheele R. [Hysterosalpingectomy. A contribution to the prevention of primary tubal neoplasms]. Fortschr Med. 1980 Jun 5;98(21):818-22. German. | |
| 9175692 | Background | Zalel Y, Lurie S, Beyth Y, Goldberger S, Tepper R. Is it necessary to perform a prophylactic oophorectomy during hysterectomy? Eur J Obstet Gynecol Reprod Biol. 1997 May;73(1):67-70. doi: 10.1016/s0301-2115(97)02702-4. |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Dec 10, 2015 | |
| Reset | Jan 14, 2016 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Dec 10, 2015 | Jan 14, 2016 |
| ID | Term |
|---|---|
| D058994 | Salpingectomy |
| D013246 | Sterilization, Tubal |
| ID | Term |
|---|---|
| D013509 | Gynecologic Surgical Procedures |
| D013519 | Urogenital Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
| D013245 | Sterilization, Reproductive |
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| 12501050 | Background | Morse AN, Hammer RA, Walter AJ, Baker S, Magtibay PM. Does hysterectomy without adnexectomy in patients with prior tubal interruption increase the risk of subsequent hydrosalpinx? Am J Obstet Gynecol. 2002 Dec;187(6):1483-5; discussion 1485-6. doi: 10.1067/mob.2002.130212. |
| 15957999 | Background | Farquhar CM, Sadler L, Harvey SA, Stewart AW. The association of hysterectomy and menopause: a prospective cohort study. BJOG. 2005 Jul;112(7):956-62. doi: 10.1111/j.1471-0528.2005.00696.x. |
| 3746790 | Background | Riedel HH, Lehmann-Willenbrock E, Semm K. Ovarian failure phenomena after hysterectomy. J Reprod Med. 1986 Jul;31(7):597-600. |
| 11788175 | Background | Bulent Tiras M, Noyan V, Ozdemir H, Guner H, Yildiz A, Yildirim M. The changes in ovarian hormone levels and ovarian artery blood flow rate after laparoscopic tubal sterilization. Eur J Obstet Gynecol Reprod Biol. 2001 Dec 1;99(2):219-21. doi: 10.1016/s0301-2115(01)00410-9. |