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Using a protective ventilation strategy during general anesthesia from pre-oxygenation to emergence and selecting patients without risk of a difficult airway or intubation, a lower fraction of inspiratory oxygen (FIO2) can be used during extubation. This might reduce the postoperative area of atelectasis without desaturations becoming more common.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 100% oxygen during extubation | Experimental | In this arm the intervention will consist of 100 % oxygen. |
|
| 30% oxygen during extubation | Experimental | In this arm the intervention will consist of 30 % oxygen. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 30% oxygen | Procedure |
| ||
| 100% oxygen |
| Measure | Description | Time Frame |
|---|---|---|
| Area of atelectasis | The area of atelectasis is investigated by computed tomography of the lungs postoperatively | 30 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Peripheral oxygen saturation (SpO2) | SpO2 is continuously assessed postoperatively. | 3 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Mats Enlund, M.D., Ph.D. | Landstinget i Värmland | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Västmanlands sjukhus Köping | Köping | Västmanland County | 731 81 | Sweden |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24720763 | Derived | Edmark L, Auner U, Lindback J, Enlund M, Hedenstierna G. Post-operative atelectasis - a randomised trial investigating a ventilatory strategy and low oxygen fraction during recovery. Acta Anaesthesiol Scand. 2014 Jul;58(6):681-8. doi: 10.1111/aas.12322. Epub 2014 Apr 11. |
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| ID | Term |
|---|---|
| D010100 | Oxygen |
| ID | Term |
|---|---|
| D018011 | Chalcogens |
| D004602 | Elements |
| D007287 | Inorganic Chemicals |
| D005740 | Gases |
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