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This study investigates if data about monitoring the drainage of pleural effusion can be collected by non invasive sensors (feasibility).
25 patients > 18 years old with pleura effusion will be examined with regard to the feasibility of non invasive sensor measurements corresponding to the course of thorax impedance and respiration parameters during body fluids loss before and after pleural drainage. The measured data will be compared to standard routine reference measurements (heart rate, medication, brain natriuretic peptide (BNP), heart minute volume). Additionally heart sound analysis via electronic stethoscope will be compared to standard methods.
Also 25 healthy controls will undergo the same measurements to receive standard values.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| non invasive sensor pleural drainage | Other | feasibility data will be collected with thorax impedance measurements via body bioimpedance sensor in Ohm before and after pleura drainage, via impedance cardiography stroke volume and cardiac output will be calculated and also respiratory parameters determined via capnograph as carbon dioxide (CO2) in %/ml exhaled volume before and after pleura drainage. Additionally heart sound analysis via electronic stethoscope will be compared to standard methods. |
|
| non invasive sensor healthy control | Other | the same measurements as in arm 1: feasibility data will be collected with thorax impedance measurements via body bioimpedance sensor before and after pleura drainage in Ohm, via impedance cardiography stroke volume and cardiac output will be calculated and also respiratory parameters determined via capnograph as carbon dioxide (CO2) in %/ml exhaled volume once in 25 healthy controls. Additionally heart sound analysis via electronic stethoscope will be compared to standard methods. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Body Bioimpedance Sensor | Device |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change of thorax impedance (Ohm) | non invasive bioimpedance measurements to determine feasibility of body fluid loss before and after pleura drainage in 25 patients > 18 years old; also 25 healthy controls are measured to receive standard values | once during hospital stay at baseline time 0 before pleura drainage and after pleura drainage at time 1 hour. |
| Measure | Description | Time Frame |
|---|---|---|
| Change of Cardiac output ( l/min) via impedance cardiography | non invasive bioimpedance measurements to determine feasibility of impedance cardiography before and after pleura drainage; also 25 healthy controls are measured to receive standard values | once during hospital stay at baseline time 0 before pleura drainage and after pleura drainage at time 1 hour |
| Measure | Description | Time Frame |
|---|---|---|
| Change of respiratory parameter CO2 in %/ml exhaled air | respiratory parameters as CO2 in %/ml exhaled volume will be determined via capnograph | once during hospital stay at baseline time 0 before pleura drainage and after pleura drainage at time 1 hour |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Nikolaus Marx, MD | Medical Clinic I, University Hospital Aachen | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Univeristy Hospital Aachen | Aachen | North Rhine Westfalia | 52074 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25861647 | Derived | Zink MD, Weyer S, Pauly K, Napp A, Dreher M, Leonhardt S, Marx N, Schauerte P, Mischke K. Feasibility of bioelectrical impedance spectroscopy measurement before and after thoracentesis. Biomed Res Int. 2015;2015:810797. doi: 10.1155/2015/810797. Epub 2015 Mar 11. |
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| ID | Term |
|---|---|
| D010996 | Pleural Effusion |
| ID | Term |
|---|---|
| D010995 | Pleural Diseases |
| D012140 | Respiratory Tract Diseases |
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