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| Name | Class |
|---|---|
| Military University Hospital, Prague | OTHER |
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Evacuation of pleural effusion (PE) represents a disputable therapy in mechanically ventilated patients. Patients on mechanical ventilation indicated by the physician to pleural fluid evacuation will be monitored throughout the procedure by electrical impedance tomography (EIT) and concurrently end-expiratory lung volume (EELV) will be measured in order to describe impact of PE evacuation on aeration and ventilation of the lungs.
Critically ill patients treated in intensive care units have a disorder of distribution and volume of body fluids due to principal illness and some therapeutic interventions. One of its manifestations is pleural effusion (PE) formation.
Patients on mechanical ventilation indicated by treating physician to pleural fluid evacuation will be monitored throughout the procedure by electrical impedance tomography (EIT) and concurrently end-expiratory lung volume (EELV) will be measured. The purpose of the study is to better understand impact of PE evacuation on aeration and ventilation of the lungs.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Electrical Impedance Tomography record | Experimental | Electrical Impedance Tomography monitoring of the pleural effusion evacuation. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Electrical Impedance Tomography record | Device | Monitoring of pleural effusion evacuation by means of EIT |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change of the thorax electrical impedance following pleural effusion drainage in mechanically ventilated patients | Comparison of EIT results with end-expiratory lung volume measurement during drainage of pleural effusion | 4 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Change of the distribution of ventilation following pleural effusion drainage in mechanically ventilated patients | Change of distribution of ventilation over EIT regions of interest (ROIs) | 4 hours |
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Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Karel Roubik, Prof., PhD. | Czech Technical University in Prague | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The Military University Hospital | Prague | 16902 | Czechia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25079591 | Background | Razazi K, Thille AW, Carteaux G, Beji O, Brun-Buisson C, Brochard L, Mekontso Dessap A. Effects of pleural effusion drainage on oxygenation, respiratory mechanics, and hemodynamics in mechanically ventilated patients. Ann Am Thorac Soc. 2014 Sep;11(7):1018-24. doi: 10.1513/AnnalsATS.201404-152OC. | |
| 9106583 | Background |
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| ID | Term |
|---|---|
| D010996 | Pleural Effusion |
| ID | Term |
|---|---|
| D010995 | Pleural Diseases |
| D012140 | Respiratory Tract Diseases |
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| Mattison LE, Coppage L, Alderman DF, Herlong JO, Sahn SA. Pleural effusions in the medical ICU: prevalence, causes, and clinical implications. Chest. 1997 Apr;111(4):1018-23. doi: 10.1378/chest.111.4.1018. |
| 21288334 | Background | Goligher EC, Leis JA, Fowler RA, Pinto R, Adhikari NK, Ferguson ND. Utility and safety of draining pleural effusions in mechanically ventilated patients: a systematic review and meta-analysis. Crit Care. 2011;15(1):R46. doi: 10.1186/cc10009. Epub 2011 Feb 2. |
| 24308560 | Background | Alves SH, Amato MB, Terra RM, Vargas FS, Caruso P. Lung reaeration and reventilation after aspiration of pleural effusions. A study using electrical impedance tomography. Ann Am Thorac Soc. 2014 Feb;11(2):186-91. doi: 10.1513/AnnalsATS.201306-142OC. |