Remote Ischemia Pre-Conditioning in Patients Undergoing Partial Nephrectomy

The Effect of Remote Ischemic Preconditioning in Partial Nephrectomy

Partial Nephrectomy has become the standard treatment in patients with tumours <7cm (T1). Even though this is a nephron sparing surgery, there is still potential for acute kidney injury, due to ischemia during the surgery. Remote Ischemia Preconditioning may prevent acute kidney injury and in turn chronic kidney disease. Remote Ischemia pre-conditioning involves applying a blood pressure cuff and inflating and deflating several times immediately prior to surgery.

Inclusion Criteria:

• Patient must be a candidate for laparoscopic partial nephrectomy
• ECOG Performance status of 0-1

Exclusion Criteria:

• No diagnosis of any current cutaneous, vascular or neural disease in the right upper arm.
• If the patient received isoflurane for any indication during the operation