Intima Media Thickness Regression in Dyslipidemic Teenagers

Intervention précoce Sur Les Indices d'athérogénèse Des Adolescents à Risque

Randomized controlled trial of statin intervention in dyslipidemic obese teenagers. Primary outcome is intima media thickness before and after intervention.

Obese teenagers with abnormal lipid profiles were randomized to either low dose statin or placebo and had their carotid intima media thickness compared before and after intervention.

Inclusion Criteria:

• Obesity
• Abnormal Triglyceride levels (>1.7mmol/L).
• Abnormal HDL-C levels (1.0mmol/L)

Exclusion Criteria:

• Abnormal thyroid unfction (not treated)
• Diabetes