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South Asians have one of the highest rates of heart disease of all populations and a unique and deleterious obesity phenotype of increased body fat and inner-abdominal compared to those of European background. We have subsequently identified that this unique phenotype accounts for much of the increased heart disease risk in South Asians, with the greater amounts of inner abdominal fat being particularly implicated. In addition, South Asians in Canada have substantially lower levels of leisure-time physical activity.
At present, we do not know the answers to the following questions:
We anticipate that both the SE and BE programs will be superior to the NE group in terms of reducing VAT and CVD risk factors. Such findings will demonstrate that exercise is an effective method that favourably modifies the obesity phenotype of excess VAT in South Asians, and should be central to health promotion and disease prevention strategies.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Non exercise control | No Intervention | Non exercise control will undergo baseline testing and follow up testing but will not participate in an exercise intervention. | |
| Standard Exercise | Experimental | The standard exercise group will attend exercise sessions under the supervision of a Certified Personal Trainer. Intensity will increase every four weeks by 10% from 50-80% of maximal heart rate to ensure that exercise is progressive in nature. Participants will be provided with a heart rate monitor during their exercise sessions and have the option to perform the aerobic training on a treadmill, upright bike, elliptical machine or recumbent bike as long as heart rate is kept within the prescribed training intensity. Intensity, duration, resting and exercise heart rates will be recorded for each exercise session for the duration of the intervention to ensure compliance to the exercise program. |
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| Bhangra Dance Exercise | Experimental | Bhangra dance classes taught be a certified instructor progressing in difficulty over the 12 week period. Bhangra dance is an Indian folk dance that consists of jumping and kicking of a high intensity. This group will attend exercise sessions under the supervision of a Bhangra Dance Instructor. The intensity of bhangra dance will be tracked through heart rate monitors worn by participants. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Standard Exercise | Behavioral | Aerobic exercise with a progressive increase in intensity over 12 weeks. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Visceral adipose tissue | Visceral adipose tissue will be assessed with multi-slice computed tomography | 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Cardiometabolic risk factors | Blood will be drawn and assessed for lipids, glucose, insulin, CRP, adiponectin and ALT | 12 weeks |
| Body Composition | DEXA scans will be used to assess body fat distribution and lean body mass |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Scott A Lear, PhD | Simon Fraser University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Simon Fraser University | Vancouver | British Columbia | V6B5K3 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26909531 | Derived | Lesser IA, Singer J, Hoogbruin A, Mackey DC, Katzmarzyk PT, Sohal P, Leipsic J, Lear SA. Effectiveness of Exercise on Visceral Adipose Tissue in Older South Asian Women. Med Sci Sports Exerc. 2016 Jul;48(7):1371-8. doi: 10.1249/MSS.0000000000000906. |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| Bhangra dance exercise | Behavioral | Bhangra Dance classes taught by an instructor. |
|
| 12 weeks |
| Maximal Aerobic Fitness | A Bruce protocol treadmill test with metabolic data will be used to assess aerobic fitness | 12 weeks |
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001519 | Behavior |