Light-Scattering Spectroscopy for Detection of Breast Cancer

Light-Scattering Spectroscopy for the Detection of Stage II-III Breast Cancer: A Pilot Study

This pilot clinical trial studies light-scattering spectroscopy in finding disease in patients with stage II-III breast cancer. Diagnostic procedures, such as light-scattering spectroscopy, may help find and diagnose breast cancer

PRIMARY OBJECTIVES: I. To evaluate whether light-scattering spectroscopy can reliably distinguish between two subject groups: those with clinical stage II or stage III breast cancer and those without breast cancer.

OUTLINE: Patients undergo light-scattering spectroscopy of the breast in addition to standard of care as it relates to screening for breast cancer or treatment of breast cancer.

Inclusion Criteria:

• Participants who are breast cancer free (mammogram "negative" within 1 month of testing) with the absence of clinical suspicion of breast cancer on physical exam or with clinical stage II or stage III breast cancer. PLEASE NOTE: Recruitment for this study is only limited to patients who are scheduled for a mammogram at USC. There is no compensation to participants.
• Provision of informed consent prior to any study-related procedures

Exclusion Criteria:

• Females with tattoos on either or both breasts
• Females with nipple piercings on either or both breasts
• Females with skin piercings (aka microdermal anchor surface or microdermal piercings) in either or both breasts
• Females unable to provide informed consent
• Females s/p treatment for breast cancer