COPD patients often suffer from dyspnea and exercise intolerance which lower their quality of life.The aim of this proposed study is to examine the effectiveness of multi-respiratory muscle training on respiratory function of COPD patients.

The respiratory muscle training is an important part of pulmonary rehabilitation. Subjects will be recruited from the chest medicine clinic of a medical center in Northern Taiwan, randomly assigned to control and experimental groups by severity status for a 12-week muscle training intervention.The outcome measures will be performed to evaluate respiratory function, depression status and quality of life at baseline, 4, 8 and 12 weeks of training.

Inclusion Criteria:

• Clinical diagnosis of Chronic Obstructive Pulmonary Disease
• Must be stable
• Never participate in respiratory muscle trainig program

Exclusion Criteria:

• Infection or acute excerbation condition
• Abdominal surgical
• Severe neuromuscular, cardiac disease or dementia