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To examine the effectiveness of a "need-based nutritional intervention" strategy in improving the nutritional and physical functional status of nursing home elderly.
Ninety-two nursing home residents aged 65 years or older and BMI <25 were randomly assigned to the intervention or control groups. Subjects in the treatment group received a soy-protein-based nutritional supplement, if his/her BMI was <24kg/m2 and nutritional score was <24 according to the Mini Nutritional Assessment. The supplementation would be suspended if both conditions were not met. At baseline and every 4 weeks up to 24 weeks, thereafter, all subjects were measured for anthropometric parameters. At baseline, 12 weeks and 24 weeks subjects were measured for blood biochemical indicators, handgrip strength and Barthel's index.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | Placebo Comparator | No intervention was given. All subjects received routine care |
|
| Received nutrition supplement as needed | Active Comparator | Subjects in this group received 50 g/day soy protein-based nutritional supplement (containing 9.5 g protein, 250 kcal energy and all essential micro-nutrients) whenever subjects BMI is below 24 and MNA score also below 24. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Nutritional supplement | Dietary Supplement | Subjects will receive 50 g/day of a soy protein-based nutritional supplement containing 9.5 g protein, 250 kcal energy and all essential micronutrients |
| Measure | Description | Time Frame |
|---|---|---|
| Assessment of nutritional status with the Mini nutritional Assessment (MNA) | Change from baseline in MNA score at 4, 8, 12, 16, 20 and 24 weeks | Baseline and every 4 weeks, up to 24 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Biochemical indicators | Change from baseline in serum albumin and cholesterol concentrations, and hemoglobin, hematocrit and lymphocyte count status at 12, and 24 weeks. | Baseline, 12, and 24 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Physical functional status | Change from baseline in Barthel's index and handgrip strength at 12 and 24 weeks | Baseline, 12 and 24 weeks |
| Hospital admissions | Frequency of outpatient visits, emergency visits and hospital admission (length of stay) during the study |
Inclusion Criteria:
Exclusion Criteria:
1.Hospitalized or having acute infection/diseases
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| Name | Affiliation | Role |
|---|---|---|
| Alan C Tsai, PhD | Professor, Dept. of Healthcare Adm., Asia University, 500 liufeng Road, Wufeng, Taichung, Taiwan 41354 | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Asia University | Taichung | 41354 | Taiwan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 11322680 | Background | Weatherall M. Protein-energy oral supplementation in malnourished nursing-home residents. Age Ageing. 2001 Jan;30(1):85. doi: 10.1093/ageing/30.1.85. No abstract available. | |
| 23648392 | Derived | Lee LC, Tsai AC, Wang JY, Hurng BS, Hsu HC, Tsai HJ. Need-based intervention is an effective strategy for improving the nutritional status of older people living in a nursing home: a randomized controlled trial. Int J Nurs Stud. 2013 Dec;50(12):1580-8. doi: 10.1016/j.ijnurstu.2013.04.004. Epub 2013 May 3. |
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| ID | Term |
|---|---|
| D044342 | Malnutrition |
| ID | Term |
|---|---|
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D019587 | Dietary Supplements |
| D013812 | Therapeutics |
| ID | Term |
|---|---|
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |
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| Treatment as usual | Other | routine care |
|
| Baseline, and 24 weeks |