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Iron deficiency and vitamin D deficiencies are common in menstruating women. The present assay studied the influence of the consumption of a flavoured skimmed milk with iron (iron pyrophosphate) or with iron and vitamin D3 in iron deficient women on:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Iron-fortified dairy product | Experimental | Consumption of an iron-fortified flavoured skimmed milk as part of the usual diet |
|
| Iron and vitamin D dairy product | Experimental | Consumption of an iron and vitamin D fortified flavoured skimmed milk as part of the usual diet |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Iron fortified flavoured skimmed milk with or without vitamin D in iron deficient women | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Ferritin changes over 16 weeks | 16 weeks (Measures at 0, 4, 8, 12 and 16 weeks) |
| Measure | Description | Time Frame |
|---|---|---|
| Haemoglobin changes over 16 weeks | 16 weeks (Measures at 0, 4, 8, 12 and 16 weeks) | |
| Total erythrocytes changes over 16 weeks | 16 weeks (Measures at 0, 4, 8, 12 and 16 weeks) | |
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Inclusion Criteria:
Exclusion Criteria:
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24663082 | Background | Blanco-Rojo R, Toxqui L, Lopez-Parra AM, Baeza-Richer C, Perez-Granados AM, Arroyo-Pardo E, Vaquero MP. Influence of diet, menstruation and genetic factors on iron status: a cross-sectional study in Spanish women of childbearing age. Int J Mol Sci. 2014 Mar 6;15(3):4077-87. doi: 10.3390/ijms15034077. | |
| 23813442 | Background |
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| ID | Term |
|---|---|
| D000090463 | Iron Deficiencies |
| ID | Term |
|---|---|
| D019189 | Iron Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D014807 | Vitamin D |
| ID | Term |
|---|---|
| D012632 | Secosteroids |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |
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| Haematocrit changes over 16 weeks |
| 16 weeks (Measures at 0, 4, 8, 12 and 16 weeks) |
| Mean corpuscular volume changes over 16 weeks | 16 weeks (Measures at 0, 4, 8, 12 and 16 weeks) |
| Red blood cell distribution width changes over 16 weeks | 16 weeks (Measures at 0, 4, 8, 12 and 16 weeks) |
| Serum iron changes over 16 weeks | 16 weeks (Measures at 0, 4, 8, 12 and 16 weeks) |
| Serum transferrin changes over 16 weeks | 16 weeks (Measures at 0, 4, 8, 12 and 16 weeks) |
| Transferrin saturation changes over 16 weeks | 16 weeks (Measures at 0, 4, 8, 12 and 16 weeks) |
| Soluble transferrin receptor changes over 16 weeks | 16 weeks (Measures at 0, 8, and 16 weeks) |
| 25-hydroxyvitamin D changes over 16 weeks | 16 weeks (Measures at 0, 8, and 16 weeks) |
| Procollagen type 1 N-terminal propeptide (P1NP) changes over 16 weeks | 16 weeks (measures at 0, 8 and 16 weeks) |
| Cross-linked N-telopeptides of type I collagen (NTX) changes over 16 weeks | 16 weeks (measures at 0, 8 and 16 weeks |
| Parathormone (PTH) changes over 16 weeks | 16 weeks (measures at 0, 8 and 16 weeks |
| Total cholesterol changes over 16 weeks | 16 weeks (Measures at 0, 8 and 16 weeks |
| LDL-cholesterol changes over 16 weeks | 16 weeks (Measures at 0, 8 and 16 weeks) |
| HDL-cholesterol changes over 16 weeks | 16 weeks (Measures at 0, 8 and 16 weeks) |
| Triglycerides changes over 16 weeks | 16 weeks (Measures at 0, 8 and 16 weeks) |
| Systolic blood pressure changes over 16 weeks | 16 weeks (Measures at 0, 8 and 16 weeks) |
| Diastolic blood pressure changes over 16 weeks | 16 weeks (Measures at 0, 8 and 16 weeks) |
| glucose changes over 16 weeks | 16 weeks (Measures at 0, 8 and 16 weeks) |
| Wright I, Blanco-Rojo R, Fernandez MC, Toxqui L, Moreno G, Perez-Granados AM, de la Piedra C, Remacha AF, Vaquero MP. Bone remodelling is reduced by recovery from iron-deficiency anaemia in premenopausal women. J Physiol Biochem. 2013 Dec;69(4):889-96. doi: 10.1007/s13105-013-0266-3. Epub 2013 Jun 28. |
| 24219374 | Result | Toxqui L, Perez-Granados AM, Blanco-Rojo R, Wright I, Gonzalez-Vizcayno C, Vaquero MP. Effects of an iron or iron and vitamin D-fortified flavored skim milk on iron metabolism: a randomized controlled double-blind trial in iron-deficient women. J Am Coll Nutr. 2013;32(5):312-20. doi: 10.1080/07315724.2013.826116. |
| 23771807 | Result | Toxqui L, Perez-Granados AM, Blanco-Rojo R, Wright I, de la Piedra C, Vaquero MP. Low iron status as a factor of increased bone resorption and effects of an iron and vitamin D-fortified skimmed milk on bone remodelling in young Spanish women. Eur J Nutr. 2014;53(2):441-8. doi: 10.1007/s00394-013-0544-4. Epub 2013 Jun 16. |
| 24317556 | Result | Toxqui L, Blanco-Rojo R, Wright I, Perez-Granados AM, Vaquero MP. Changes in blood pressure and lipid levels in young women consuming a vitamin D-fortified skimmed milk: a randomised controlled trial. Nutrients. 2013 Dec 5;5(12):4966-77. doi: 10.3390/nu5124966. |
| 24886470 | Result | Toxqui L, Perez-Granados AM, Blanco-Rojo R, Wright I, Vaquero MP. A simple and feasible questionnaire to estimate menstrual blood loss: relationship with hematological and gynecological parameters in young women. BMC Womens Health. 2014 May 30;14:71. doi: 10.1186/1472-6874-14-71. |