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A previous study demonstrated topical lidocaine spray on the larynx and the trachea is effective in reducing hemodynamic response to laryngoscopy and endotracheal intubation. In clinical practice, blind oropharyngeal application of lidocaine without aiding direct laryngoscopy can not assured that sprayed lidocaine effectively reaches the larynx and trachea. Therefore, direct laryngoscopy should be necessary to reach topical lidocaine to correct sites. Unfortunately, direct laryngoscopy itself can affect hemodynamics during spraying lidocaine. In this study, we will investigate an effect of lidocaine sprayed on direct laryngoscopy and the tracheal mucosa on hemodynamic change throughout intubation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| group L | Experimental | 10% Lidocaine was applied to the laryngoscope blade and 0.9% normal saline was applied to the trachea. |
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| group C | Placebo Comparator | 0.9% normal saline was applied to trachea and laryngoscope blade in Group C. |
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| group V | Experimental | 0.9% normal saline was applied to the laryngoscope blade and 10% Lidocaine was applied on trachea. |
|
| group LV | Experimental | 10% Lidocaine was applied on laryngoscope blade and trachea. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| group C | Drug | 0.9% normal saline was applied to trachea and laryngoscope blade |
| |
| Measure | Description | Time Frame |
|---|---|---|
| mean blood pressure, heart rate | baseline, at laryngoscope insertion, 60s after laryngoscope insertion, during intubation, one, two, three min after endotracheal intubation |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| SUE YOUNG LEE, MD | Contact | 82-10-9700-6509 | tndude49@hanmail.net |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Hospital | Recruiting | Seoul | Seoul | 110-744 | South Korea |
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| group L |
| Drug |
10% Lidocaine was applied to the laryngoscope blade and 0.9% normal saline was applied to the trachea. |
|
| group V | Drug | 0.9% normal saline was applied to the laryngoscope blade and 10% Lidocaine was applied on trachea. |
|
| group LV | Drug | 10% Lidocaine was applied on laryngoscope blade and trachea. |
|