Multidetector Computed Tomography (MDCT) Tailored Protocol

A Multicenter, Multinational, Randomized Study of Standard vs. Patient-Adapted Protocols in Multidetector Computed Tomography (MDCT) of the Chest, Abdomen, Liver or Aorta

Collection of data from different sites regardless of whether they use standard or tailored protocols for the application of high concentration iodinated contrast agents to assess if the individually patient-adapted protocols result in a similar diagnostic image quality.

To record technical information and compare image quality regarding routine MDCT procedures with contrast administration using a tailored contrast injection and radiation dose protocol. The hypotheses are that the tailored protocols lead to a lower applied mean radiation dose compared to the use of standard protocols and will provide a more standardized contrast dose per patient size without impairing diagnostic quality.

Inclusion Criteria:

• At least 18 years of age
• Scheduled to undergo contrast enhanced MDCT of the abdomen, liver, aorta, or chest
• Provides written informed consent

Exclusion Criteria:

• Previously enrolled and completed the study
• Known allergy to iodinated contrast media
• Pregnancy or lactation
• Clinically unsuitable for the study