Metabolism Associated With Abdominal Fat Mass Distribution

Metabolism Associated With Abdominal Fat Mass Distribution

Objectives:

The primary objective of this clinical trial is to characterize metabolic signatures associated with abdominal fat distribution in 40 women with different BMI 29-40 and different abdominal distribution of fat (visceral vs. sub-cutaneous fat).

No intervention with a product is planned. The subjects will be given one high fat meal with commercial products (eggs, milk, cream, bread, fruits, cheese and cheese) on one test day to test the post-prandial metabolic response.

Inclusion Criteria:

• BMI 29-40 kg/m2
• Aged 25-45

Exclusion Criteria:

• Diagnosed metabolic disorder such as Diabetes type 1 and 2, cardiovascular disease, metabolic syndrome
• Pregnancy
• Any pathology (infectious or other) having required an antibiotic therapy within 1 month prior to the beginning of the study.
• Any therapy (contraception apart) within the run-in period of one week before the test day.
• Subject who cannot be expected to comply with treatments and measures.
• Subject who is affected by any specific eating disorder
• Currently participating or having participated in another clinical trial during the last 3 months prior to the beginning of this study.
• Subjects having recently undergone a weight loss of more than 3 kilos during the last 3 months