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While CBT (Cognitive Behaviour Therapy)has been found to be effective in treating depression in West, only limited amount of research has been conducted to find assess its effectiveness in low and middle income countries. We have developed culturally sensitive CBT during the last few years in Pakistan. Pakistan has high rates of depression. And there is currently a need to develop and test evidence based treatments which are culturally sensitive and cost effective. IN this project we will be assessing the effectiveness of a culturally sensitive CBT based self help intervention for depression in Pakistan against care as usual, using a randomized controlled design.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Culturally adapted CBT based Self Help | Experimental | Culturally sensitive cbt based self help intervention, which consists of 6 regular chapters and 2 additional chapters. The self help intervention involves family to improve compliance with the intervention |
|
| Care As Usual | No Intervention | Control Group |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Culturally adapted CBT based Self Help | Behavioral | Intervention was based on our initial work using mixed methods, using mixed methods,in Pakistan. It focused on psycho-education, symptoms management, changing negative thinking, behavioral activation, problem solving, improving relationships and communication skills. One person from the family was involved in all cases. The intervention consists of 7 chapters. Manual can be used by the patient's or carers with at least 5 years of education. A member of the research team called them once every week to remind them of the next chapter and also to discuss any issues o problems that emerged during the previous week. This manual can be downloaded from PACT website (http://www.pactorganization.com/) |
| Measure | Description | Time Frame |
|---|---|---|
| Hospital Anxiety and depression Rating Scale- Depression subscale | Measurement of depression | Participants will be assessed at baseline and then end of therapy at 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Hospital Anxiety and Depression Scale, Anxiety subscale | Measurement of anxiety | Participants will be assessed at baseline and then end of therapy at 12 weeks |
| Bradford Somatic Inventory | Measurement of somatic symptoms |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Mehwish Khalid, MSc | PACT | Study Director |
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| ID | Term |
|---|---|
| D003863 | Depression |
| ID | Term |
|---|---|
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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| Participants will be assessed at baseline and then end of therapy at 12 weeks |
| Brief disability questionnaire | To measure disability associated with depression | Participants will be assessed at baseline and then end of therapy at 12 weeks |