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| Name | Class |
|---|---|
| Institute for Human Development and Potential (IHDP), Singapore | OTHER |
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Using fMRI, this study will explore the neural correlates of satiety when individuals make decisions about food. The investigators will also examine individual differences in satiety effects.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Low disinhibition | fMRI during fed and fasted states | ||
| High disinhibition | fMRI during fed and fasted states |
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| Measure | Description | Time Frame |
|---|---|---|
| fMRI - Willingness to Pay task (BDM auction) | A measurement of how much participants are willing to pay for foods and non-foods, as an assay for subjective value of goods. | Fed and fasted visits (Wks 1 & 2) |
| fMRI - Monetary and Food Incentive Delay task | A measurement of neural response to anticipating and receiving money and food rewards. | Fed and fasted visits (Wks 1 & 2) |
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Inclusion Criteria:
Exclusion Criteria:
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Community sample
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| Name | Affiliation | Role |
|---|---|---|
| Michael WL Chee, MBBS | Duke-NUS Graduate Medical School | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre for Cognitive Neuroscience scanner suite | Singapore | Singapore | 169611 | Singapore |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 17855612 | Background | Plassmann H, O'Doherty J, Rangel A. Orbitofrontal cortex encodes willingness to pay in everyday economic transactions. J Neurosci. 2007 Sep 12;27(37):9984-8. doi: 10.1523/JNEUROSCI.2131-07.2007. | |
| 10875899 | Background | Knutson B, Westdorp A, Kaiser E, Hommer D. FMRI visualization of brain activity during a monetary incentive delay task. Neuroimage. 2000 Jul;12(1):20-7. doi: 10.1006/nimg.2000.0593. |
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| ID | Term |
|---|---|
| D005215 | Fasting |
| D007863 | Lecithin Cholesterol Acyltransferase Deficiency |
| ID | Term |
|---|---|
| D005247 | Feeding Behavior |
| D001519 | Behavior |
| D052456 | Hypoalphalipoproteinemias |
| D007009 | Hypolipoproteinemias |
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(NA)
| D008052 |
| Lipid Metabolism, Inborn Errors |
| D008661 | Metabolism, Inborn Errors |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D050171 | Dyslipidemias |
| D052439 | Lipid Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |