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Observational cohort study in children hospitalized for acute bronchiolitis. Patients are nursed in cohort isolation. Aim is to investigate the incidence and clinical impact of co-infections in this group.
Observational cohort study in children hospitalized for acute bronchiolitis. Patients are nursed in cohort isolation, meaning that all patients admitted for bronchiolitis are cohorted together, irrespective of viral diagnosis. Aim is to investigate the incidence and clinical impact of co-infections in this group.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| cohort isolation | patients with bronchiolitis are cohorted together irrespective of viral agent diagnosed, thus respiratory syncytial virus (RSV)-positive patient stay in the same room as RSV-negative patients |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| cohort isolation | Other | all patients hospitalised for bronchiolitis are nursed in one room together, separated from patients without bronchiolitis |
|
| Measure | Description | Time Frame |
|---|---|---|
| co-infection | co-infection acquired during hospitalisation, patient will be followed during hospitalisation and until 1 week after discharge from the hospital, since average duration of hospitalisation in infants with bronchiolitis is 3 days, the time frame will be approximately 2 weeks | approximately 2 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| clinical severity | clinical severity defined as, days of oxygen supplementation, tube feeding, dyspnea score, length of hospitalisation | approximately 2 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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children < 2 years admitted for bronchiolitis
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| Name | Affiliation | Role |
|---|---|---|
| Jolita Bekhof, MD | Isala | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Isala Klinieken | Zwolle | Overijssel | 8000 GK | Netherlands |
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| ID | Term |
|---|---|
| D001988 | Bronchiolitis |
| ID | Term |
|---|---|
| D001991 | Bronchitis |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D001982 | Bronchial Diseases |
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sputum tested for viral agents by PCR-techniques
| D012140 |
| Respiratory Tract Diseases |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |