Prognostic and Predictive Biomarkers of Therapeutic Response in Pancreatic Tumors

Research for Prognostic and Predictive Biomarkers of Therapeutic Response in Pancreatic Tumors - PACAomics / IPC 2011-004

Pancreatic cancer is among the most serious human neoplasia and the most difficult to treat.

Most patients present at diagnosis a non resectable, locally advanced or metastatic disease, with a median survival of 12 month.

The aim of this study is the identification of diagnosis biomarkers, predictive of the therapeutic response.

This project investigate the use of molecular analyses applied to pancreatic tumor cells collected by microbiopsy under ultrasound-endoscopy, and blood cells.

Inclusion Criteria:

• Suspicion of pancreatic adenocarcinoma
• Patient > 18 years old
• Social Security affiliation
• Signed informed consent

Exclusion Criteria:

• Patient in emergency situation
• Major person being the object of a legal protective measure or unable to express its consent