Short and Long-term Safety of Micafungin and Other Parenteral Antifungal Agents

A Multicenter Cohort Study of the Short and Long-term Safety of Micafungin and Other Parenteral Antifungal Agents

This multicenter observational cohort study proposes to establish the risks of short and long-term outcomes in users of parenteral micafungin and in users of other parenteral antifungal agents from 2005 through 2012 with follow-up until 2017.

All eligible patients treated with a parenteral antifungal agent at any time during the years 2005-2012 in each of the participating hospitals, will be included in the study.

Inclusion Criteria:

• hospitalized and treated with parenteral antifungal medication
• first time treatment of the patient with parenteral antifungal in the medical center was anytime from 2005 through 2012

Exclusion Criteria:

• prior diagnosis of hepatocellular carcinoma
• had received parenteral antifungal therapy during the 6 months prior to index hospitalization